Malaria
Conditions
Interventions
Malaria episodes management
Artesunate-Amodiaquin
Sponsors
Malaria Research and Training Center/Faculty of Medecine and Dentistry/University of Sceinces, Techniques and Technologies
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children aged 6-15 years; - Enrolled in basic school Sirakoro Meguètana; - Available and able to follow-up study visits; - Do not show any general danger signs (inability to drink, uncontrollable vomiting, history of convulsion, lethargy, inability to sit unaided) or other signs of severe and complicated malaria falciparum according to the criteria of WHO; - Obtaining informed consent from child parents or guardian; - No history of hypersensitivity reactions to study drugs reported ;
Exclusion criteria
Exclusion criteria: - Presence of biological abnormalities identified at enrollment - Presence of any acute illness - Presence of chronic diseases (diabetes, High blood pressure etc.). - Presence of an evident pregnancy or revealed by a biological test - History of antimalarial treatment (ACTs or other) within 15 days before enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Malaria incidence defined by the number of epidoses of uncomplicated malaria in the group receiving SMC compared to the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of anemia defined by the proportion of children with a Hb level <10g/dl in both groups 2. Safety : measured by the proportion of children who had an AE or SAE 3. Acceptability of the approach as measured by a questionnaire sent to teachers and students asking their views on the disadvantages, advantages, and their adherence to the approach. 4. School success/completion rates | — |
Countries
Mali
Contacts
Public ContactOgobara Doumbo
Director/MRTC/DEAP/FMOS/USTTB
Outcome results
None listed