postoperative analgesia following total knee arthroplasty

Effect of dexamethasone added to bupivacaine for femoral nerve block on the quality of postoperative analgesia following total knee arthroplasty: A randomized, double blinded, controlled study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201407000850309

Enrollment

200

Registered

2014-07-08

Start date

2014-08-28

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery postoperative pain Orthopaedics Anaesthesia

Interventions

bupivacaine 0.5 %

0.5% bupivacaine plus dexamethasone

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- patients having osteoarthritis 2- age above 50 3- ASA 1,2,3 patients 4-both sexes

Exclusion criteria

Exclusion criteria: contraindication to peripheral nerve block (femoral nerve block),ASA IV or V, peripheral neuropathy, acute intercurrent heart disease; chronic opiate use, and known allergic reaction to local an aesthetics, paracetamol or morphine; skin lesions/infection at block site; renal dysfunction, and Patients with systemic infections

Design outcomes

Primary

Measure	Time frame
time to the first analgesia required for pain at the surgical sight;the amount of morphine required in the first 24 hours and comparing the total amount of morphine used in the two studied groups	—

Secondary

Measure	Time frame
numerical rating pain score (NRS) from 0 (no pain) to 10 (worst pain imaginable) both at rest and on flexion of the operated knee	—

Countries

Egypt

Contacts

Public ContactHazem Elsersy

Lecturer of Anethesia, Faculty of medicine,Menoufia University

hazelsersy@hotmail.com00201222598999

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026