The effectiveness of dexamethasone as an adjunct to surgery on satisfactory resolution of chronic subdural haematomas: A randomised control trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201406000799322

Enrollment

Registered

2014-03-24

Start date

2014-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases Surgery Chronic subdural haematomas

Interventions

Dexamethasone

Placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age above 18 2. Chronic subdural haematoma diagnosed on CT Scan requiring surgical management as determined by the neurosurgeon.

Exclusion criteria

Exclusion criteria: 1. Patients who are already on corticosteroids for other reasons 2. Patients with contraindications for corticosteroid use 3. Patient refusal 4. Patients who require early (within 6 weeks) re-commencement of antiplatelet or anti-coagulant therapy as determined by the physician

Design outcomes

Primary

Measure	Time frame
Satisfactory Radiological Resolution	—

Secondary

Measure	Time frame
1) To compare the proportion of patients with clinical resolution via a Markwalder Grading Scale to assess neurological outcome ;2) To compare the proportion of patients with residual collection requiring a second operation;3) To determine frequency of complications from steroid use	—

Countries

Kenya

Contacts

Public ContactCarnjini Yogeswaran

Resident In Surgery

carnjini.yogeswaran@aku.edu+254717022905

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026