Effectiveness of an alcohol-focused intervention in improving adherence to antiretroviral therapy (ART) and HIV treatment outcomes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201405000815100

Enrollment

604

Registered

2014-04-22

Start date

2014-11-03

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS

Interventions

MI-PST for alcohol

MI-PST for mutrition

Treatment as usual

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) are HIV-positive; (2) have taken ART for at least three months; (3) are not currently receiving treatment for TB (or latent TB infection); (4) are 18 years or older; (5) are classified as ¿harmful/hazardous drinkers¿ (AUDIT score of 8-22); (6) are resident in the Tshwane Metropolitan Municipality;

Exclusion criteria

Exclusion criteria: 1) have substantial cognitive impairment; (2) are currently enrolled in another trial; and (3) have extremely poor general health/functional status (Karnofsky clinical score > 50).

Design outcomes

Primary

Measure	Time frame
reductions in the volume of alcohol consumed	—

Secondary

Measure	Time frame
Reductions in AUDIT scores;reductions in Ethyl Glucuronide (EtG) and Posphatidylethanol (PEth) scores ;increase in Antiretroviral adherence rates;reductions in HIV RNA viral loads;increases in CD4 T-cell counts.	—

Countries

South Africa

Contacts

Public ContactNeo Morojele

Deputy Director

neo.morojele@mrc.ac.za00 27 12 3398535

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026