Respiratory Paediatrics pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children with ¿ acute bacterial lobar or bronchial pneumonia, ¿ aged between one month and eight years ¿ hospitalised in Red Cross War Memorial Children¿s Hospital, Cape Town ¿ tachypnoea (RR ¿ 20 breaths per minute (bpm) in children > five years, ¿ 40 bpm in children between one and five years, ¿ 50 bpm in children between two and 12 months, and ¿60 bpm in children < two months) ¿ fever and/or cough ¿ radiological confirmation of pneumonia ¿ clinically stable (unstable = on mechanical ventilation, on positive pressure ventilation, tachycardia (<1year = 160 beats/min, 1-2year = 150 beats/min, 3-4year = 140 beats/min, 5-12years = 120 beats/min) or inadequate blood pressure, altered mental status, oxygen saturation <90% on oxygen support; when a child has none of these symptoms, then he/she is considered clinically stable)
Exclusion criteria
Exclusion criteria: -Active tuberculosis (TB), -Bronchiolitis, -Pneumocystis jirovecii pneumonia (suspected or proven), -Pleural effusion, -Recent pneumothorax in last three months, -Asthma, -Increased intracranial pressure, -Chest deformities, -Osteoporosis, -Severe hypoxia or distress (oxygen saturation < 90% on oxygen and clinical signs: cyanosis, weak cry, feeding problems and head nodding, nasal flaring). If the child has more than 3 signs of severe distress or hypoxia, it will be excluded. If the child has 3 or less signs it will be included if the child is clinically stable. -Cystic fibrosis (these children are standardly hospitalised for two weeks which influences the duration of hospitalisation), -Other chronic respiratory disease which require daily physiotherapy -Presence of an intercostal drain, -Currently receiving mechanical ventilation, -Thoracic or abdominal surgery in the preceding six months, -Severe heart defect -Premature: < 30 weeks of gestation, -Hospitalised for less than 2 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration of hospitalisation | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of fever;respiratory rate;lung function test (children >5years);oxygen saturation;duration of supplemental oxygen;atelectasis/collaps;progression of respiratory support;mortality rate | — |
Countries
South Africa
Contacts
PhD-student