Surgery Paediatrics cancer Anaesthesia
Conditions
Interventions
ketofol (1:1 mixture of propofol and ketamine)
MK group
Sponsors
ADEKOLA LATEEF
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ASA I-II children aged 1-15 years undergoing procedural sedation and analgesia for haematological malignancy All consecutive children with haematological cancer undergoing bone marrow aspiration/biopsy and lumbar puncture (LP) for chemotherapy in the paediatric oncology ward
Exclusion criteria
Exclusion criteria: prior sensitization or allergic reaction to propofol, ketamine, soy or egg products presences of hypotension, head injury, increased intracranial increased intraocular pressure use of drugs known to interact with any of the study agent patients who have been involved in another study in the last 30 days. Patients with heart, lung or neurological disease, and central nervous system disorders symptomatic thrombocytopenia, age less than 1 year or over 15 years ASA IV-V patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.A change less than or greater than 20% change in Heart Rate 2.A change less than or greater than 20% in Respiratory Rate 3.Systolic blood pressure greater than the fifth percentile of normal for age 4.Systolic blood pressure less than the fifth percentile of normal for age 5.Movement during sedation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine if spontaneous ventilation continues following administration of the anaesthetic agents for sedation. 2. Pain (Yes/No), the participant will be monitored from the end of the procedure until sedation recovery | — |
Countries
Nigeria
Contacts
Public ContactE Temiye
Professor of Paediatric Oncology/ Lagos University Teaching Hospital
Outcome results
None listed