Digestive System Paediatrics Acute Gastroenteritis
Conditions
Interventions
Racecadotril +standard WHO treatment ( ORS, Zinc, continued feeding)
Placebo + Standard WHO treatment ( ORS, Zinc, Continued feeding)
Sponsors
Aga Khan University
Sai Pharmaceuticals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children 3mo ¿ 60mo Acute gastroenteritis as defined by WHO (the passage of unusually loose or watery stools, usually at least three times in a 24 hour period) requiring admission for severe gastroenteritis (as evidenced by a vesicari score of >11) parental consent obtained
Exclusion criteria
Exclusion criteria: Scoring 3 on the vesicari score for Maximum Number Vomiting Episodes per Day Clinical diagnosis of dysentery Requiring / having been prescribed antibiotics and/or probiotics or any other anti-diarrhoeal medication for the disease (except zinc) known diagnosis of liver and renal failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| severity of the diarrhoeal illness, measured by the number of stools in the first 48 hours after introduction of the drug and the consistency of stools at 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| the duration of inpatient stay ;number of adverse events associated with racecadotril | — |
Countries
Kenya
Contacts
Public ContactJaspreet Singh Gharial
3rd year postgraduate resident
Outcome results
None listed