A TRIAL COMPARING PROPHYLACTIC PHENYLEPRINE FIXED DOSE VERSES A WEIGHT ADJUSTED DOSE IN REDUCING HYPOTENSION FOLLOWING SPINAL ANAESTHESIA FOR CAESERE

A RANDOMIZED CONTROL TRIAL COMPARING WEIGHT ADJUSTED DOSE VERSUS FIXED DOSE PROPHYLACTIC PHENYLEPRINE INFUSION ON MAINTAINING SYSTOLIC BLOOD PRESSURE DURING CAESEREAN SECTION UNDER SPINAL ANAESTHESIA.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201403000636418

Enrollment

130

Registered

2013-09-05

Start date

2013-07-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Surgery Hypotension following spinal anaesthesia for caeserean section. Anaesthesia

Interventions

prophylactic phenyleprine fixed dose infusion

weight adjusted dose

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All ASA I and II patients over 18years scheduled for non-urgent caesarean delivery.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Patients with contraindications to neuraxial anaesthesia a. Puncture site infection b. Hypovolemic shock c. Coagulopathy d. Sepsis 3. Patient involved in any other clinical studies 4. Women scheduled for emergency c\s 5. Type 1 DM 6. HPTN/Cardiac disease

Design outcomes

Primary

Measure	Time frame
Compare the incidence of hypotension between the two study groups	—

Secondary

Measure	Time frame
Porportion of bradycardia and reactive hypertension between the two study groups; Number of physician interventions between the two study groups	—

Countries

Kenya

Contacts

Public ContactSamina Mir

Obstetric Anaesthesiologist

samina.mir@aku.edu+254726720473

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026