TARGET-CONTROLLED INFUSION OF PROPOFOL-FENTANYL VERSUS DESFLURANE ON HEPATOCELLULAR INTEGRITY IN CIRRHOTIC PATIENTS UNDERGOING MAJOR HEPATIC RESECTION

EFFECT OF TARGET-CONTROLLED INFUSION OF PROPOFOL-FENTANYL VERSUS DESFLURANE ON HEPATOCELLULAR INTEGRITY IN CIRRHOTIC PATIENTS UNDERGOING MAJOR HEPATIC RESECTION

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201402000759256

Enrollment

Registered

2014-02-02

Start date

2012-02-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System Surgery Hepatocellular carcinoma Anaesthesia

Interventions

TARGET CONTROLLED INFUSION

INHALATIONAL

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patient. Cirrhotic patient. Child A classified patient.

Exclusion criteria

Exclusion criteria: - history of esophageal disease. - Patients undergoing re-operation. - history of allergic reactions to drugs. - recent anaesthetia (within the previous 7 days). - Patients who bled profusely during their operation, who are haemodynamically unstable, or who need inotropic support. - preoperative renal dysfunction

Design outcomes

Primary

Measure	Time frame
Liver function test [glutathione S transferase];Kidney function test [microalbumin in urine]	—

Secondary

Measure	Time frame
Hemodynamic parameters[corrected flow time,stroke volume,systemic vascular resistance	—

Countries

Egypt

Contacts

Public ContactElsayedamr Basma

Patient information Manager

elsayedamr@yahoo.com002-01223106023

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026