Tourniquet Hypertension

A RANDOMISED CONTROL TRIAL TO ASSESS THE EFFECT OF A KETAMINE INFUSION ON TORNIQUET HYPERTENSION DURING GENERAL ANAESTHESIA IN PATIENTS UNDERGOING UPPER AND LOWER LIMB SURGERY.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201402000718234

Enrollment

Registered

2013-12-03

Start date

2012-10-08

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Tourniquet hypertension Anaesthesia

Interventions

Ketamine infusion

saline group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ¿American Society of Anaesthesiologists (ASA) physical status I and II patients ¿Patients undergoing elective and emergency orthopaedic surgery with tourniquet application under general anaesthesia

Exclusion criteria

Exclusion criteria: ¿ASA physical status III and above ¿Age below 18yrs and above 70 yrs ¿Pregnant women ¿Surgery performed under regional anaesthesia ¿Patients with hypertension, ischaemic heart disease and diabetes mellitus ¿Patients with dementia or a history of a psychiatric illness ¿Patients who refuse to give consent

Design outcomes

Primary

Measure	Time frame
Intra- operative blood pressure changes from baseline values	—

Secondary

Measure	Time frame
heart rate changes associated with tourniquet use, efficacy of ketamine on post-op pain and incidence of side effects associated with ketamine use	—

Countries

Kenya

Contacts

Public ContactCiru Kamanda

Research Assistant

kamanda.ciru@aku.edu+254203662958

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026