Sisters Antiretroviral therapy Programme for Prevention of HIV ¿ an Integrated Response (SAPPH-IRe)

Conditions

HIV/AIDS

Cowan FM, Davey C, Fearon E, Mushati P, Dirawo J, Chabata S, Cambiano V, Napierala S, Hanisch D, Wong-Gruenwald R, Masuka N, Mabugo T, Hatzold K, Mugurungi O, Busza J, Phillips A, Hargreaves JR.

2018-07-1885 citations

10.1016/s2352-3018(18)30111-5

Statistical design and analysis plan for an impact evaluation of an HIV treatment and prevention intervention for female sex workers in Zimbabwe: a study protocol for a cluster randomised controlled trial

James Hargreaves, Elizabeth Fearon, Calum Davey, Andrew Phillips, Valentina Cambiano et al. (6 authors)

Trials2016-01-0525 citations

10.1186/s13063-015-1095-1

Interventions

Enhanced ART for prevention intervention

Usual Care

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: ¿Age 18 or older ¿Currently working as a sex worker (has exchanged sex for money in the past 30 days) ¿Living or working in the study site (for at least 6 month)

Exclusion criteria

Exclusion criteria: ¿ Under 18 ¿ Already participated in the current round of survey ¿Visiting the study site temporarily (for less than 6 month) ¿Not currently working as a sex worker (verification questions will be used to prevent fraudulent participation, such as about how sex work is organised in the area and the cost of different sex acts)

Design outcomes

Primary

Measure	Time frame
Proportion of all SW (including those HIV-negative) who are infectious with HIV (HIV infected and viral load > 1000 copies/mL)	—

Secondary

Measure	Time frame
Proportion of HIV-infected women who are infectious;ii. Proportion of those taking ART who have viral load >1000 who have drug resistance;Incidence of HIV infection in the 6 month period before the endline survey;Proportion adherence to ART for treatment;Self-reported quality of life, psychological health and functioning;Proportion of SWs always using condoms with clients in last month;Proportion of SWs who know HIV status (ie are diagnosed HIV positive or were tested HIV negative in last 6 months);Proportion of sex workers offered, initiating and, where appropriate, adhering to ART;Proportion of sex workers offered, initiating and, where appropriate, adhering to PrEP	—

Measure

Time frame

Proportion of HIV-infected women who are infectious;ii. Proportion of those taking ART who have viral load >1000 who have drug resistance;Incidence of HIV infection in the 6 month period before the endline survey;Proportion adherence to ART for treatment;Self-reported quality of life, psychological health and functioning;Proportion of SWs always using condoms with clients in last month;Proportion of SWs who know HIV status (ie are diagnosed HIV positive or were tested HIV negative in last 6 months);Proportion of sex workers offered, initiating and, where appropriate, adhering to ART;Proportion of sex workers offered, initiating and, where appropriate, adhering to PrEP

—

Countries

Zimbabwe

Contacts

Public ContactSibongile Mtetwa

Project Director

sibo@ceshhar.co.zw+263 772 288169

Outcome results

None listed