Effect of amlodipine on blood flow of preovulatory follicle in Polycystic ovarian patients: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201309000638372

Enrollment

Registered

2013-09-05

Start date

2013-01-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility-female infertility

Interventions

Amlodipine

placebo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: a) Demographic features including age of ¿20 & ¿35 BMI of ¿39 b) Infertility secondary to PCO, as indicated by amenorrhea or oligomenorrhea, elevated serum LH levels, normal or low FSH levels, elevated LH/FSH ratio, clinical evidence of androgen excess (acne, hirsutism, alopecia), elevated serum levels of testosterone , ultrasound findings of enlarged ovaries with multiple small cysts (10-12 or more of 2-9 mm in diameter) scattered around the periphery and highly echogenic stroma.

Exclusion criteria

Exclusion criteria: other causes of infertility diagnosed during infertility work up, also, hepatic, cardiac, and hypotensive patients

Design outcomes

Primary

Measure	Time frame
progesteron level;peak systolic velocity, Pulsatility indices and resistant indices of ovarian (vessel supplying preovulatory follicle) and uterine;size of dominant follicle or follicles	—

Secondary

Measure	Time frame
endometrial thickness;pregnancy rate	—

Countries

Egypt

Contacts

Public ContactDoaa Abdelmageed Saleh;Osama Mahmoud El Faham;Azmy

Specialist in National Research Centre;Professor of obestetrics and gynecology

drdody_as@hotmail.com;osamazmy@yahoo.com002 0109 589 36 24;002 0122 31 03084

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026