The Effect of Melatonin on Osseointegration Of immediate Loading Implant supported Mandibular Overdentures

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201307000557125

Enrollment

Registered

2013-06-06

Start date

2013-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Health bone loss

Interventions

topical application of melatonin in the implant site

No melatonin application

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Completely edentoulous patient 2. sufficient inter arch space(14mm-18mm 3. All patients had normal maxillo-mandibular relationship (Class I Angle classification) 4.All patients were physically and psychologically able to tolerate conventional implant surgical protocol.

Exclusion criteria

Exclusion criteria: 1.Patients with diabetes that may affect bone resorption 2. Pregnancy. 3.Presence of acute and active infection or inflammation in areas intended for implant placement.

Design outcomes

Primary

Measure	Time frame
measuring bone density	—

Secondary

Measure	Time frame
implant stability	—

Countries

Egypt

Contacts

Public ContactAlaa Aboul Ela

Professor of Prothodontics

dr_alaa_aboulela@hotmail.com01222151949

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026