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Induction of labour in women with term premature rupture of membranes.

Oxytocin versus concurrent use of oxytocin and rectal misoprostol for induction of labour in women with term premature rupture of membranes:A randomised controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201211000447393
Enrollment
110
Registered
2012-10-30
Start date
2012-09-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth Induction of labour in pregnant women with term premature rupture of membranes.

Interventions

Group A
Group B

Sponsors

Department of Obstetric and Gynecology
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Confirmed gestational age (32-42 weeks gestation)determined last menstrual period or by ultrasound scan in the 1st trimester. A singleton pregnancy with normal fetus in vertex presentation. Premature rupture of membranes confirmed by visualizing a pool of amniotic fluid at a sterile speculum examination and AFI less than 5. Absence of other indications for urgent induction of labor No signs of active labor, no abdominal pain on admission.

Exclusion criteria

Exclusion criteria: Known hypersensitivity or any contraindications to prostaglandins (e.g.gluoma or sickle cell disease). Multiple pregnancy. Multiparity Contraindication to vaginal birth such as previous uterine surgery, contracted pelvis or malpresentation. Estimated fetal weight more than 4 kg or less than 2 kg Placenta previa or unexplained vaginal bleeding. Evidence of chorioamnionitis. Medical diseases e.g. cardiovascular disease or chronic renal failure.

Design outcomes

Primary

MeasureTime frame
The number of women who will succeed in delivering vaginally

Secondary

MeasureTime frame
Incidence of excess uterine activity,labor induction to delivery interval, meconium stained liquor and mode of delivery

Countries

Egypt

Contacts

Public ContactAlaa Masoud

Lecturer in Obstetrics and Gynecology (Menoufiya University)

Alaa_masoud75@hotmail.com002 01001545759

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Aug 9, 2026