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The efficacy of prophylactic antibiotics in the management of pneumonitis following paraffin ingestion in children

The efficacy of prophylactic antibiotics in the management of pneumonitis following paraffin ingestion in children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201201000259370
Enrollment
200
Registered
2010-10-28
Start date
2010-07-21
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury, Occupational Diseases, Poisoning Respiratory Paediatrics paraffin poisoning

Interventions

Amoxicillin
Placebo

Sponsors

Dr Kate Balme
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Ingested paraffin in the preceding 24 hours Presence of respiratory symptoms or signs Informed consent by parent/legal guardian Resident within the hospital drainage area and able to come for 2 follow up appointments

Exclusion criteria

Exclusion criteria: 1. Asymptomatic and no clinical signs 2. Too ill to be excluded from receiving an antibiotic as judged by: o Requiring more than 2L/min nasal-prong oxygen o Requiring continuous or intermittent positive airway pressure ventilation o Fever > 40 degrees Celsius 3. Needing an antibiotic for another reason e.g. otitis media, tonsillitis 4. Current antibiotic use, prior to kerosene ingestion 5. Allergic to amoxicillin

Design outcomes

Primary

MeasureTime frame
Treatment failure

Secondary

MeasureTime frame
Length of stay in hospital ;Reported symptoms and clinical signs, specifically related to the respiratory system

Countries

South Africa

Contacts

Public ContactKate;Kate Balme;Balme

;

kate.balme@uct.ac.za;kh.balme@uct.ac.za021 658 5308;021 658 5308

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026