Clinical care bundles for adult meningitis in Malawi

Early Goal Directed Therapy for adult meningitis in Malawi

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR201111000338157

Enrollment

200

Registered

2011-11-11

Start date

2012-01-02

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial meningitis

Interventions

Clinical care bundle

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary inclusion criteria: Fever plus one of headache confusion coma seizures Secondary inclusion criteria: CSF white cell count >50 cells per mm2, irrespective of HIV status, or visible bacteria in the counting chamber or on Gram's stain

Exclusion criteria

Exclusion criteria: Primary exclusion criteria: Known terminal illness Cerebral malaria Head trauma Secondary exclusion criteria CSF culture stain or antigen positive for an organim known to cause fungal or mycobacterial menignitis CSF WCC <50% neutrophils

Design outcomes

Primary

Measure	Time frame
Percentage of clinical targets achieved by the care bundle	—

Secondary

Measure	Time frame
Mortality;Neurological disability;Seizure frequency	—

Countries

Malawi

Contacts

Public ContactTamara Chipasula

tchipasula@mlw.medcol.mw+2651876444

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026