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Using mobile-phone based text messages to improve retention of patients initiating antiretroviral therapy in South Africa

Using mobile-phone based text messages to improve retention of patients initiating antiretroviral therapy in South Africa

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR201105000299318
Enrollment
1200
Registered
2011-05-16
Start date
2011-06-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS

Interventions

SMSs
Standard Care

Sponsors

Canadian International Development Agency (CIDA)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are 18 years of age or older. Patients who are initiating ART. Patients who own or have access to a mobile phone with functional text message features. Patients who can receive text messages. Patients who can read text messages. Patients who agree to continue their ART at the site at which they were initiated for 12 months. In other words, the patient will not be down referred to a local community clinic during the study.

Exclusion criteria

Exclusion criteria: Patients who reside in an area where there is no mobile network reception. Patients who plan to relocate away from the area or transfer to another antiretroviral treatment facility during the next 12 months. Patients who are enrolled in other concurrent research studies designed to investigate the effect of mobile-phone based text message reminders to improve retention in treatment. Patients who belong to a household within which another individual has already enrolled for the study.

Design outcomes

Primary

MeasureTime frame
Retention;Treatment Interruptions

Secondary

MeasureTime frame
Clinical outcome: HIV-1 RNA viral load and CD4 T-lymphocyte count;patient medication self-efficacy;commitment to treatment;perceived social support;disclosure of HIV status;interpersonal relationships;experienced stigma and depression;optimistic self-beliefs about health benefits of ART;awareness of possible adverse effects and toxicity;knowledge of difficulties experienced during ART initiation;lifestyle changes for improved health outcomes

Countries

South Africa

Contacts

Public ContactSarah Brown

Project Manager and Co-Principal Investigator

Sarah@cell-life.org27 (0)21 469-1111

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026