Tuberculosis
Conditions
Interventions
Xpert arm
Control arm
Sponsors
University of Cape Town
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult patients presenting to the study clinics for TB investigation, including both: 1. Patients with suspected TB; and 2. Patients with suspected drug-resistant TB, including patients suspected of failing TB treatment
Exclusion criteria
Exclusion criteria: Patients currently on TB therapy and undergoing testing for treatment monitoring purposes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients with untreated TB two months after enrolment (untreated TB defined as patients with TB diagnosed by smear or culture at the 2 month follow up visit, but not before, or patients in whom the diagnosis of TB had been confirmed (smear, culture or Xpert) previously but who had not yet commenced TB treatment at the 2 month follow up visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to appropriate TB treatment (defined as time between enrolment and commencement of appropriate first line or drug-resistant TB treatment);Mortality (all cause);Time to diagnosis (defined as the time between enrolment and a confirmed diagnosis of TB based on smear, culture or Xpert);Number of clinic visits prior to appropriate TB treatment | — |
Countries
South Africa
Contacts
Public ContactMark Nicol
Outcome results
None listed