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GRASP

Gastric Residual volume Assessment using ultrasound in Supine heads-up Position for thick fluids in the mechanically ventilated ICU population. - GRASP

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON61372
Enrollment
81
Registered
2025-12-11
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delayed gastric emptying, increased gastric residual volumes. Delayed gastric emptying, increased gastric residual volumes.

Interventions

All study participants receive antral ultrasounds in supine and right lateral decubitus position once during the first 5 days of admission, while they also receive the standard care with syringe aspir

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
16 Years to 99 Years

Inclusion criteria

Inclusion criteria: Admission to the intensive care unit no more than five days ago. 16 years or older. Must have a gastric feeding tube in place, either nasogastric, orally or percutaneous.Receives enteral nutrition.Invasive mechanical ventilationMedically stable situation to be able to receive decubitus prevention by alternating positions

Exclusion criteria

Exclusion criteria: Patients having undergone an esophagectomy, gastric bypass, or other surgery altering anatomy of the gaster. Pregnant woman past the 20th week of pregnancy.Known upper gastric area anatomical problem (such as but not limited to; pancreatitis, large amounts of ascites, cancer, perforation, hiatal hernia).Patients with known withdrawal of life support within 24 hours. 

Design outcomes

Primary

MeasureTime frame
The primary objective is to construct an ultrasound guided mathematical model for determining GRV in supine heads-up position in the mechanically ventilated ICU population receiving enteral nutrition using the existing model for right lateral decubitus position for thick fluids as the golden standard aiming for a mean difference of within 25ml.

Secondary

MeasureTime frame
Reliability and feasibility of syringe aspiration via gastric feeding tube compared with ultrasound assessment of GRV in supine position for measuring GRV and diagnosing gastric intestinal disfunction defined as GRV >500ml/6 hours.Investigate the possibility of a specific cut-off point in gastric antral cross-sectional area, anteroposterior diameter or craniocaudal diameter that correlates with the need for prokinetics in both supine heads-up position and right lateral decubitus position, specifically GRV of >300ml in 4 hours and >500ml in 6 hours.Assess the possibility of verifying gastric feeding tube placement via ultrasound in order to reduce radiation load if classic verification, by use of potentia hydrogenii (PH) of GRV, is not possible.

Countries

Netherlands

Contacts

Public ContactM. Bochove - Waardenburg

Erasmus MC, Universitair Medisch Centrum Rotterdam

m.waardenburg@erasmusmc.nl010-704-07-04

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026