Delayed gastric emptying, increased gastric residual volumes. Delayed gastric emptying, increased gastric residual volumes.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Admission to the intensive care unit no more than five days ago. 16 years or older. Must have a gastric feeding tube in place, either nasogastric, orally or percutaneous.Receives enteral nutrition.Invasive mechanical ventilationMedically stable situation to be able to receive decubitus prevention by alternating positions
Exclusion criteria
Exclusion criteria: Patients having undergone an esophagectomy, gastric bypass, or other surgery altering anatomy of the gaster. Pregnant woman past the 20th week of pregnancy.Known upper gastric area anatomical problem (such as but not limited to; pancreatitis, large amounts of ascites, cancer, perforation, hiatal hernia).Patients with known withdrawal of life support within 24 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to construct an ultrasound guided mathematical model for determining GRV in supine heads-up position in the mechanically ventilated ICU population receiving enteral nutrition using the existing model for right lateral decubitus position for thick fluids as the golden standard aiming for a mean difference of within 25ml. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reliability and feasibility of syringe aspiration via gastric feeding tube compared with ultrasound assessment of GRV in supine position for measuring GRV and diagnosing gastric intestinal disfunction defined as GRV >500ml/6 hours.Investigate the possibility of a specific cut-off point in gastric antral cross-sectional area, anteroposterior diameter or craniocaudal diameter that correlates with the need for prokinetics in both supine heads-up position and right lateral decubitus position, specifically GRV of >300ml in 4 hours and >500ml in 6 hours.Assess the possibility of verifying gastric feeding tube placement via ultrasound in order to reduce radiation load if classic verification, by use of potentia hydrogenii (PH) of GRV, is not possible. | — |
Countries
Netherlands
Contacts
Erasmus MC, Universitair Medisch Centrum Rotterdam