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Omega Fatty Acids and Muscle Outcomes

The Effect of Omega-3 Supplementation on Muscle Damage, Soreness, and Fatigue in Healthy Volunteers - Omega Fatty Acid–Enriched Protein Products and Muscle Outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON61284
Enrollment
110
Registered
2026-01-12
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle damage, soreness and fatigue muscle injuiry, aches and tiredness

Interventions

Participants will be randomly assigned to one of two groups. The control group will receive no supplement. The intervention group will receive an&nbsp
omega-3 supplement containing 1 g of omega-3 fatty acids. This omega-3 supplement will be consumed for three weeks prior to and during the Nijmegen Four Days Marches.

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 18 years or olderRegistered for the Nijmegen Four Days Marches (i.e., able to walk 30-50 km on consecutive days)Able to understand and perform the study procedures

Exclusion criteria

Exclusion criteria: Current use of omega-3 supplements (e.g. fish oil or algae oil)Allergic or sensitive for  algae products (source of omega-3). 

Design outcomes

Primary

MeasureTime frame
Muscle damage measured by circulating creatine kinase is the primary outcome. 

Secondary

MeasureTime frame
Secondary outcomes are muscle soreness measured by a VAS-scale and pressure pain threshold; muscle fatigue measured with a VAS-scale.

Countries

Netherlands

Contacts

Public ContactMaria Hopman

Radboud Universitair Medisch Centrum

maria.hopman@radboudumc.nl(024) 361 42 73

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 3, 2026