How do patients and (informal) caregivers view a new surgical treatment for Alzheimer’s disease?

Qualitative participatory research on perceptions surrounding the implementation of a surgical treatment for Alzheimer’s disease (lymphovenous anastomosis) - Qualitative participatory research on perceptions surrounding the implementation of a surgical treatment for Alzheimer’s disease (lymphovenous anastom

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON61260

Enrollment

Registered

2026-04-14

Start date

2026-08-30

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's Disease, Alzheimer's Dementia, AD, Cognitive Disorder, neurodegenerative diseases Alzheimer's Disease, Alzheimer's Dementia

Interventions

There is no research product or intervention involved

this is an observational qualitative study of perceptions regarding a hypothetical surgical treatment (LNVA) for Alzheimer’s disease.&nbsp

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with early-stage dementiaDiagnosis of mild cognitive impairment or early-stage dementia.Age = 18 years.Able to participate in a group discussion.Sufficient proficiency in the Dutch language.Willingness to provide written informed consent.Informal caregiversInformal caregiver of a person with dementia.Age = 18 years.Sufficient proficiency in the Dutch language.Willingness to participate in a focus group.Healthcare professionalsWorking in the care of people with dementia (e.g., neurologist, geriatrician, psychiatrist, nurse, dementia case manager).At least one year of work experience in this field.Willingness to participate in a focus group.

Exclusion criteria

Exclusion criteria: Insufficient proficiency in the Dutch language.Severe cognitive impairment preventing participation in a group discussion.Individuals unable to provide informed consent.Individuals unwilling to allow audio recording of the discussion.

Design outcomes

Primary

Measure	Time frame
As the study is qualitative in nature, no clinical outcome measures are assessed; instead, thematic outcomes are explored.Primary outcome measures: Participants’ perceptions regarding the potential use of a lymphovenous anastomosis as a treatment for Alzheimer’s disease, including:Perceived acceptance of a surgical treatmentExpectations regarding potential effectivenessConcerns about risks and complications	—

Measure

Time frame

As the study is qualitative in nature, no clinical outcome measures are assessed; instead, thematic outcomes are explored.Primary outcome measures: Participants’ perceptions regarding the potential use of a lymphovenous anastomosis as a treatment for Alzheimer’s disease, including:Perceived acceptance of a surgical treatmentExpectations regarding potential effectivenessConcerns about risks and complications

—

Secondary

Measure	Time frame
Secondary outcome measures:Perceived burden of a potential surgical interventionConditions for participation in future clinical researchFactors influencing acceptance of the interventionPreconditions for implementation in clinical practicePreferences regarding information provision and informed consentVariables: age, participant role (patient, caregiver, healthcare professional), professional background (for healthcare professionals), years of experience in dementia care (for healthcare professionals)	—

Measure

Time frame

Secondary outcome measures:Perceived burden of a potential surgical interventionConditions for participation in future clinical researchFactors influencing acceptance of the interventionPreconditions for implementation in clinical practicePreferences regarding information provision and informed consentVariables: age, participant role (patient, caregiver, healthcare professional), professional background (for healthcare professionals), years of experience in dementia care (for healthcare professionals)

—

Countries

Netherlands

Contacts

Public ContactB.F.M. Rijken

Maastricht Universitair Medisch Centrum +

linde.jacobs@mumc.nl+31652824191

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jun 29, 2026