Corticospinal Control of Gait Corticospinal Control of Gait
Conditions
Interventions
Healthy individuals aged between 18 and 40 years, with no history of musculoskeletal, neurological, or vestibular disorders, will be included in the study. All participants must meet the necessary eli
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Be between 18 and 40 years of age Be healthy, defined as having no known neurological, psychiatric, or other medical condition that may interfere with safe participation, walking performance, or the interpretation of TMS/EMG/gait outcomes.
Exclusion criteria
Exclusion criteria: Currently pregnant A history of or 1st degree family members (parents, siblings, children) with epilepsy, convulsions or seizures Past brain surgery A pacemaker or intra-cardiac wires An implanted neurostimulator Cochlear implants Implanted medication infusion device Broken skin in the area to be contacted Multiple sclerosis Large ischaemic scars Increased intracranial pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During normal, laterally stabilized, narrow-base and wide-base walkingnormal and laterally stabilized walking, TMS will be applied to elicit MEPs in the lower limb muscles. In addition, kinematic and kinetic parameters related to gait will be recorded using a motion capture system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome parameters, including gait stability, step width, step length, stride duration, and foot placement control (R²), will be analyzed using within-subject comparisons between the normal and stabilized walking conditions. Data distributions will first be assessed for normality using the Shapiro–Wilk test. For normally distributed data, paired-sample t-tests will be applied; for non-normally distributed data, the Wilcoxon signed-rank test will be used. | — |
Countries
Netherlands
Contacts
Public ContactA.I. Ilez
Vrije Universiteit
Outcome results
None listed