nausea, acute nausea, nausea symptoms, nausea and quesiness, feeling sick, gatrointestinal discomfort, nausea with or without vormiting, emesis, tendency to vormit. nausea, feeling nauseous, feeling quesy, feeling sick
Conditions
Interventions
Patients will receive either an IPA swab (intervention) or a saline swab (placebo) for nasal inhalation, in addition to standard care antiemetics. IPA or placebo swabs will be used as often as desired
Sponsors
Frisius Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients =18 year with a self-rated nausea score of = 3 on a VNRS scale (0-10) in the ED.
Exclusion criteria
Exclusion criteria: A known allergy to isopropyl alcoholInability to inhale through the noseA reduced level of consciousness or any other medical condition hindering following study instructions and providing informed consent. Inability to speak, read or write in Dutch or EnglishPregnant womenpatients undergoing active oncological treatmentPrior treatment with isopropyl alcohol (IPA) inhalation before arrival at the emergency department for the current presentation (e.g. prehospital administration by ambulance services)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the reduction in nausea (VNRS score) 10 minutes after the first inhalation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include nausea reduction at 30 minutes, and every 30 minutes thereafter during ED stay, incidence of vomiting, and the use of additional antiemetics. | — |
Countries
Netherlands
Contacts
Public ContactS.L. Haak
Frisius Medisch Centrum
Outcome results
None listed