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CMR for lesion visualization after PFA for AF

Cardiac Magnetic Resonance for lesion visualization after pulsed field ablation for atrial fibrillation - CMR for lesion visualization after PFA for AF

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON58585
Enrollment
50
Registered
2026-01-18
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation Atrial fibrillation

Interventions

A single CMR scan will be performed at least three months after ablation.&nbsp

Sponsors

Hagaziekenhuis, Den Haag
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Participants must be 18 years or older, diagnosed with atrial fibrillation and treated with pulmonary vein isolation using pulsed field ablation. 

Exclusion criteria

Exclusion criteria: Being unable to provide informed consent, contra-indications to cardiac MRI or catheter ablation, previous catheter ablation for atrial fibrillation, congenital heart disease, recent myocardial infarction or decompensated heart failure, prosthetic heart valves, impaired renal function (GFR < 30 ml/min/1.73 m2), pregnancy

Design outcomes

Primary

MeasureTime frame
The main study parameters are the amount of left atrial fibrosis after pulsed field ablation for paroxysmal atrial fibrillation and whether gaps are seen in the circumferential lesions around the pulmonary veins. 

Secondary

MeasureTime frame
Secondary study parameters will include left atrial parameters, specifically volumes, ejection fractions and strain measurements. Recurrence of atrial fibrillation between the ablation and CMR acquisition will be recorded. Adverse events will be recorded. 

Countries

Netherlands

Contacts

Public ContactSC Rier

Hagaziekenhuis, Den Haag

cardioresearch@hagaziekenhuis.nl070-2106987

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: May 22, 2026