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Exploratory study to investigate in-vitro extracellular trap release and to assess the in-vitro effects of various inhibitors of extracellular trap release - Citymap

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON58581
Enrollment
100
Registered
2025-12-08
Start date
2026-07-29
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

not applicable not applicable

Interventions

None listed

Sponsors

Citryll B.V.
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults between 18–75 years of age Healthy volunteer Able to give informed consent

Exclusion criteria

Exclusion criteria: Participants cannot use any medication other than oral anti contraceptives, over-the-counter medication, prescribed medication for hypertension and hypercholesterolemia Adults who smoke cannot participate

Design outcomes

Primary

MeasureTime frame
Primary Outcome measuresPresence of ET components CitH3, defined as above LLOQ (0.3 ng/mL).Inhibition of ET components defined as a reduction of 50%.

Secondary

MeasureTime frame
Secondary Outcomes measuresInduction of cytokines defined as more than two-fold compared to the negative control.

Countries

Netherlands

Contacts

Public ContactN Keijzer

Citryll B.V.

nkeijzer@citryll.com+31 629469491

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 25, 2026