not applicable not applicable
Conditions
Interventions
None listed
Sponsors
Citryll B.V.
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Adults between 18–75 years of age Healthy volunteer Able to give informed consent
Exclusion criteria
Exclusion criteria: Participants cannot use any medication other than oral anti contraceptives, over-the-counter medication, prescribed medication for hypertension and hypercholesterolemia Adults who smoke cannot participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome measuresPresence of ET components CitH3, defined as above LLOQ (0.3 ng/mL).Inhibition of ET components defined as a reduction of 50%. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcomes measuresInduction of cytokines defined as more than two-fold compared to the negative control. | — |
Countries
Netherlands
Contacts
Public ContactN Keijzer
Citryll B.V.
Outcome results
None listed