Gut microbiome modulation in healthy adults How does food influence gut bacteria in healthy volunteers
Conditions
Interventions
Vegetable smoothies prepared with crops from either high-diversity or low-diversity soil.
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age between 18–70 yearsResident of Leiden or have a regular presence in Leiden (e.g work, study)Written informed consent
Exclusion criteria
Exclusion criteria: Any documented causes of chronic diseaseSuspicion of or present excessive alcohol use defined as > 2 units/day (>14/ week).Recent use (< 3 months) of antibiotics Any known food allergy or restriction, or following a vegan/ vegetarian dietuse of possible drugs interfering microbiota or recent (< 3 months) changes in dosagesRecent (< 3 months) weight change (>5%) A psychiatric, addictive or any other disorder that compromises the participants ability to understand the study content and to give written informed consent for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of protocol implementation, including logistics, participant compliance, and sampling. | — |
Secondary
| Measure | Time frame |
|---|---|
| Exploratory analysis of gut microbiome composition, stool metabolites, and metabolic/inflammatory markers. | — |
Countries
Netherlands
Contacts
Public ContactPWJ maljaars
Leids Universitair Medisch Centrum
Outcome results
None listed