Grow It! research

Grow It!: A smartphone application to promote mental well-being among adolescents with a chronic somatic condition - Grow it - Multi site E-Health

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON58557

Enrollment

200

Registered

2025-02-17

Start date

2026-07-01

Completion date

Unknown

Last updated

2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental well-being Mental well-being

Interventions

Participants will be randomized into two groups (i.e., intervention or waitlist control group).&nbsp

All participants complete a questionnaire at baseline (T0). The intervention group then uses the Grow It! app for 28 days. Both groups complete follow-up questionnaires at T1 (immediately after the in

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: Aged between 10 and 18 Have a chronic somatic condition: a condition that lasts longer than 3 months or recurs more than three times a year and/or is related to long-term use of medication, treatments or help (van Hal et al., 2019)Have a smartphoneBe able to understand how the app works and complete the questionnaires

Exclusion criteria

Exclusion criteria: Insufficient comprehension of the Dutch language Already participated in another study that used the Grow It! app

Design outcomes

Primary

Measure	Time frame
The primary objective of this study is to examine the effect of Grow It! app version 2.0 on symptoms of anxiety and depression in youth with chronic somatic condition immediately after the intervention (T1), and at three-month (T2) and six-month (T3) follow-up, compared to the symptoms of anxiety and depression at baseline, using a parallel group RCT. Symptoms of anxiety are measured with the anxiety subscale of the Hospital Anxiety and Depression Scale. Symptoms of depression are measured with the short form of the Child Depression Inventory-2.	—

Measure

Time frame

The primary objective of this study is to examine the effect of Grow It! app version 2.0 on symptoms of anxiety and depression in youth with chronic somatic condition immediately after the intervention (T1), and at three-month (T2) and six-month (T3) follow-up, compared to the symptoms of anxiety and depression at baseline, using a parallel group RCT. Symptoms of anxiety are measured with the anxiety subscale of the Hospital Anxiety and Depression Scale. Symptoms of depression are measured with the short form of the Child Depression Inventory-2.

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Secondary

Measure	Time frame
The second objective is to examine the effect of Grow It! app version 2.0 on other psychological outcomes (using both the questionnaire data and the ESM data), underlying mechanisms of change (i.e., coping, emotional insight and self-reflection) and parental perspectives, and to explore the effect of individual differences (i.e., demographic and risk factors) on the effectiveness of the Grow It! app. The third objective is to investigate the cost-effectiveness of Grow It! in improving Health-Related Quality of Life (HRQoL) and well-being in adolescents with a chronic somatic condition. To help achieve this objective, two new questionnaires, one based on a validated adult version, and one based on a theoretical framework, were developed: the MHQoL-Y and the Well-Y. The data collected in this study will therefore also be used to validate these questionnaires.The fourth objective is to assess the user experience of Grow It! 2.0.	—

Measure

Time frame

The second objective is to examine the effect of Grow It! app version 2.0 on other psychological outcomes (using both the questionnaire data and the ESM data), underlying mechanisms of change (i.e., coping, emotional insight and self-reflection) and parental perspectives, and to explore the effect of individual differences (i.e., demographic and risk factors) on the effectiveness of the Grow It! app. The third objective is to investigate the cost-effectiveness of Grow It! in improving Health-Related Quality of Life (HRQoL) and well-being in adolescents with a chronic somatic condition. To help achieve this objective, two new questionnaires, one based on a validated adult version, and one based on a theoretical framework, were developed: the MHQoL-Y and the Well-Y. The data collected in this study will therefore also be used to validate these questionnaires.The fourth objective is to assess the user experience of Grow It! 2.0. 

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Countries

Netherlands

Contacts

Public ContactP Noorlag

Erasmus MC, Universitair Medisch Centrum Rotterdam

p.noorlag@erasmusmc.nl0643123471

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: May 16, 2026