Preoperative and intraoperative markers for prediction postoperative delirium

Early prediction of postoperative delirium after non-cardiac surgery with preoperative and intraoperative markers; a prospective observational study (EPISODE) - Preoperative and intraoperative markers for prediction of postoperative delirium

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON58556

Enrollment

450

Registered

2025-04-28

Start date

2024-07-31

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium, cognitive impairment, confusion, disorientation confusion, disoriented

Interventions

Bispectral Inde Montoring System (Medtronic): It collects raw EEG data. This device is routine in general anesthesia. However, in the study we collect bilateral data instead of unilateral.Delirium Obs

KATZ ADL: The scale is used to assess a person's ability to perform activities of daily living&nbsp

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients who are at least 60 years or olderSurgery under general anesthesiaExpected duration surgery at least 60 minutesWritten informed consent  

Exclusion criteria

Exclusion criteria: Patient undergoing emergency procedure (surgery <24 hours)Patient undergoing neurosurgeryPatient undergoing cardiac surgery, in need of Extracorporeal Membrane Oxygenation (ECMO)Severe cognitive impairment, unable to sign informed consentEEG measurements not possibleNeuropsychiatric comorbidity, unable to sign informed consentNot able to speak/understand Dutch languageHearing impairment which makes telephone interview impossible 

Design outcomes

Primary

Measure	Time frame
Incidence of post operative delirium within 1-5 days and during admission	—

Secondary

Measure	Time frame
Incidence of post operative cognitive impairment after 3 months	—

Countries

Netherlands

Contacts

Public ContactM Buise

Maastricht Universitair Medisch Centrum +

marc.buise@mumc.nl0433877457

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 25, 2026