Retinal dystrophy, inherited retinal disease Inherited eye disease
Conditions
Interventions
MicroperimetryFull-field stimulus test (FST)Visual evoked potentials (VEP)Visual field testingVisual acuity measurementsQuestionnaire on perceived visual quality (MRDQ)Target search task incorporating
Sponsors
Amsterdam UMC
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis of retinitis pigmentosa and age < 16 yearsWritten informed consent provided by parent(s) or legal guardian; for children aged 12 years and older, assent from the child is also requiredWilling to participate in both test sessions
Exclusion criteria
Exclusion criteria: Unwillingness or inability to undergo repeated ophthalmic examinations.Presence of any other ocular or systemic condition that could interfere with visual function.Concurrent participation in another clinical study involving the use of an unregistered investigational product that could affect ocular health or visual functionKnown allergy or intolerance to ophthalmic anesthetic drops (oxybuprocaine) or mydriatic agents (tropicamide and/or phenylephrine)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the test-retest reliability of the visual functional parameters | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlations between patient-reported vision-related functioning and objective visual function test resultsFeasibility and acceptability of performing the visual function tests in the paediatric population | — |
Countries
Netherlands
Contacts
Public ContactS.B.A.E. Tulp
Amsterdam UMC
Outcome results
None listed