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IMPROVE

Individualized magnetic stimulation for post-stroke cognitive recovery optimization: A viability exploration - IMPROVE

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON58508
Enrollment
25
Registered
2025-02-17
Start date
2026-06-24
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Stroke

Interventions

TMS disruption

Sponsors

Universitair Medisch Centrum Utrecht
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Age = 18 years; 2. First-ever ischemic stroke or intracerebral haemorrhage in a cerebral hemisphere or the brainstem; 3. Cognitive impairment based on assessment by the treating rehabilitation physician.  4. Able to perform n-back task at inclusion. 5. Inclusion possible within 10 weeks after stroke onset; 6. Signed informed consent. 

Exclusion criteria

Exclusion criteria: 1. Known cognitive impairment prior to stroke onset; 2. Absolute contra-indication to TMS: Magnetic sensitive objects implanted in the head or neck area (e.g. cochlear implants, implanted neurostimulator, pacemaker or defibrillator, metal splinters, metal fragments or metal clips), history of epilepsy, pregnancy or other contra-indications that may potentially be harmful as determined by the treating rehabilitation physician; 3. Incompetence or severe impairments that can impede study participation as determined by the treating rehabilitation physician (i.e. extreme fatigue, severe communication deficits); 4. Life expectancy shorter than one year. 

Design outcomes

Primary

MeasureTime frame
n-back test performance

Countries

Netherlands

Contacts

Public ContactJJ Vink

Universitair Medisch Centrum Utrecht

j.j.vink-5@umcutrecht.nl0634959811

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026