CRPS CRPS
Conditions
Interventions
The intervention under evaluation is thoracic sympathetic blockade with botulinum toxin type A, performed as part of routine clinical care. The present study does not introduce a new clinical interven
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age = 18 years at the time of the procedure.Diagnosis of CRPS according to the International Association for the Study of Pain (IASP) “Budapest Criteria,” or previously met these criteria and is now classified as “CRPS with Remission of Some Features.”Underwent a thoracic sympathetic block with botulinum toxin at Erasmus MC.
Exclusion criteria
Exclusion criteria: Thoracic sympathetic block performed with any co-medication or adjunctive intervention other than botulinum toxin, for example pulsed radiofrequency or radiofrequency ablation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measures are:pain intensity on a 0 to 10 numeric rating scale, expressed as change from baseline to available follow-up moments;limb temperature difference, affected versus contralateral, expressed as change in asymmetry from baseline;safety, including the number and type of adverse events and procedural complications. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are patient global impression of change, PGIC, changes in CRPS features within the Budapest domains, duration of effect, time until return toward baseline or additional intervention, and prior CRPS treatments and responses. Additional descriptive variables include demographics, baseline clinical characteristics, and procedural details. | — |
Countries
Netherlands
Contacts
Public ContactJ. Brink
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed