Metabolic health, obesity, shift work Obesity and night shift work
Conditions
Interventions
We aim to recruit 
100 night shift workers per center (n=200 in the Netherlands, 100 via ErasmusMC, 100 via WUR), aged 21 years or older and working for more than 24 hours per week in either the health care or non-healt
Participants in the intervention group will all follow the 24-week CLIP, designed to improve 
health behaviors in the four targeted domains. Every 6 weeks participants will focus on two components, where they receive lifestyle advice and behavioral change techniques throughout a mobile app and
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Age = 21 years Work = 24 hours per week Shift work duration > 3 years and currently doing night shifts Expected to continue night shiftwork for at least 1 year after inclusion On average working = 4 night shifts per month Working generally = 2 consecutive night shifts, or at least one night shift per month followed by another shift In possession of a smartphone and willing to download the study application
Exclusion criteria
Exclusion criteria: Body Mass Index (BMI) < 18.5 or > 40 kg/m2 Pregnant or lactating Chronic diseases if in ongoing therapy but not after a remission (renal failure, active hepatitis, cirrhosis, myocardial infarction, chronic obstructive pulmonary disease and cancer). Current or recent use of medications interfering with sleep, including: Central nervous system stimulants (e.g., Ritalin, Adderall, Modafinil or similar) Chronic use of sleep agents (e.g., benzodiazepine, non-hypnotic benzodiazepine, first-generation antihistamine, melatonin receptors agonists or similar) Other medication or combinations significantly affecting sleeping patterns Recent or ongoing psychotherapy for sleep disorders Current or recent use of medications affecting with appetite or weight regulation, including: Appetite-enhancing/weight-gain medications (e.g., atypical antipsychotics, corticosteroids such as prednisone, mirtazapine or similar) Appetite-suppressing/weight-loss medications (e.g., CNS stimulants such as Ritalin, Adderall, GLP-1 receptors agonists or similar) Other medication or combinations significantly influencing appetite or body weight Participation in another human trial, lifestyle program or weight loss intervention within the past 3 months Planned surgical procedure during the study period History of or planned bariatric surgery/treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this randomized controlled trial is to determine the effect of the CLIP on objectively measured sleep duration among night shift workers, compared to the control condition. The primary study parameter is objectively measured sleep duration (TST), expressed as minutes of total sleep time per 24-hour period at the end of the intervention (T2), assessed using actigraphy (MotionWatch 8). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objective is to explore whether the CLIP improves lifestyle behaviors in shift workers across the four targeted domains. These include: Sleep-related behavior Dietary behaviorPhysical activity Perceived stress To explore the behavioral, lifestyle, and dietary mechanisms underlying the health risks of shift work, physiological outcomes and related biomarkers (e.g. BMI, glucose, and lipid values) are included as tertiary outcomes. | — |
Countries
Netherlands
Contacts
Public ContactM. Schuring
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed