Postprandial glycemic responses Aftermeal blood sugar responses
Conditions
Interventions
a carbohydrate-rich fruit smoothie containing either 0, 21 or 42 grams of Fermofine
Sponsors
The Protein Brewery
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age 50-80yrs BMI >25 kg/m2 Having veins suitable for blood sampling via a catheter Having one or more of the following criteria:HbA1c> 5.7% Fasting glucose >5.6mmol/LTwo-hour glucose levels >7.8 mmol/L on the 75-g oral glucose tolerance test
Exclusion criteria
Exclusion criteria: Having a disease that may interfere with the outcomes of the study, such as a known metabolic, gastrointestinal, inflammatory or chronic disease as judged by the medical supervisorHaving a history of medical or surgical events that may significantly affect the study outcome, as judged by the medical supervisor (medical investigator) Use of medication that may interfere with the study outcomes, such as medication known to affect glucose homeostasis (as judged by medical investigator) Reported to follow or having planned a slimming or medically prescribed diet; Reported weight loss or weight gain of more than 3 kg in the month prior to pre-study screening, or intention to lose weight during the study period; Recent blood donation (<1 month prior to test day 1 of the study) or not willing to stop donation during and 1 month after the study Current smokers, or stopped smoking in the last 3 months before study startAverage alcohol intake >21 (women) or >28 (men) glasses of alcoholic beverages per week Use of drugs Food allergies for products that we use in the study including fungiParticipation in any other clinical trial including blood sampling and/or administration of substances up to 30 days before test day 1 of this study and during the study periodBeing an employee of the Food, Health & Consumer Research group of Wageningen Food & Biobased Research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial glucose (PPG) response (incremental area under the curve) | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to peak and maximum peak height of postprandial blood glucose responses Incremental area under the curve, time to peak and maximum peak height of postprandial insulin responses | — |
Countries
Netherlands
Contacts
Public ContactS Haar
Wageningen Universiteit
Outcome results
None listed