na na
Conditions
Interventions
The intervention is a fiber mixture selected in Phase 1 based on the group analysis. In the other period, participants receive a placebo (without active fibers).
Sponsors
TNO
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Men and women aged between 30 and 60 yearsBMI between 25 and 30 kg.m-2Low fiber intake in habitual diet (<18g/d for females and <22g/d for males)Able to communicate in Dutch and/or English
Exclusion criteria
Exclusion criteria: Evidence of any chronic disease or condition that can interfere with, or for which the treatment might interfere with the conduct of the study including but not limited to diabetes mellitus, autoimmune disease, cardiovascular disease and history of abdominal surgery Use of medication such as antibiotics, statins, or anti-diabetic drugsVegan, macrobiotic, slimming diet or dietary changes within last 3 monthsAllergies to study productsHistory of substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the gut microbiome. | — |
Secondary
| Measure | Time frame |
|---|---|
| · Effects on well-being and mood. · Additional measures: gut transit time, satiety, 6-minute walking test, and dietary intake. | — |
Countries
Netherlands
Contacts
Public ContactFPM Hoevenaars
TNO
Outcome results
None listed