Bipolar disorder Manic depressive disorder
Conditions
Interventions
A virtual Reality task (Richies plank) is used to evoke emotions associated with increased activation like excitement, arousal, tension, and elation. All participants do the task. 
Sponsors
Altrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a participant must meet all of the following criteria: - Age: 18 years or older - Sufficient proficiency in either Dutch or English, both written and spoken, to understand study materials and follow instructions during the study Patient group specific criteria: - Meet DSM-V criteria for bipolar disorder I based on patient file and confirmed by their primary caregiver, either a certified psychologist or psychiatrist.
Exclusion criteria
Exclusion criteria: A potential participant who meets any of the following criteria will be excluded from participation in this study: Criteria that might interfere with autonomic or cardiovascular responses - Known cardiovascular disease or current use of cardiovascular medication, including but not limited to beta-blockers - Current or suspected pregnancy as self-reported by the participant - Participants used drugs or alcohol 12h prior to the experiment - Participant drank, ate or smoke/vaped 2 hours prior to the experiment Group variables - Participants with acute manic or depressed mood (as determined by their mental health professional) - Advanced experience with VR - Self-reported fear of heights - For non-patient participants: first-degree relative with history of bipolar disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A comparison between a group with Bipolar I disorder and healthy controls in response to the task will be made. Specifially, change in affect (measured with VAS-scales) and physiology (heart rate variability and blood pressure) at four timepoints, namely at baseline, after instruction (anticipation phase), after the VR-task (activation), and in rest (recovery) will be measured. | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Contacts
Public ContactVFJ Glas
Altrecht
Outcome results
None listed