Impact van Centralizatie op Chirurgische Uitkomsten bij Kinderen met Anorectale Malformaties

Impact of Centralization of Care on Outcomes of Anorectal Malformation Surgery in Pediatric Patients – A Retrospective Cohort Study - Impact of Centralization of Care on Outcomes of Anorectal Malformation Surgery in Pediatric Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON58322

Enrollment

170

Registered

2026-01-15

Start date

2026-01-17

Completion date

Unknown

Last updated

2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorectal malformation Anorectal malformation

Interventions

Anorectal malformation surgery, including anoplasty, ASARP, PSARP, LAARP and PSARVUP +/- TUM.

Eligibility

Age

No minimum to 17 Years

Inclusion criteria

Inclusion criteria: All children (aged 0-18) receiving anorectal malformation surgery in either the Wilhelmina or Amalia children's hospitals between january 2014 and december 2023.

Exclusion criteria

Exclusion criteria: Children without a 90-day follow-up available without specified reason.

Design outcomes

Primary

Measure	Time frame
Textbook outcome, defined as meeting all of the following criteria: No postoperative mortality. No serious postoperative complications (exceeding a severity of Clavien-Madadi score of 2 or higher). No readmission to any hospital within 90 days of the initial surgery, with the exception of planned ostomy removal. No extended length of stay (LOS) beyond the 75th percentile of the entire cohort (i.e., 8 days).	—

Measure

Time frame

Textbook outcome, defined as meeting all of the following criteria: No postoperative mortality. No serious postoperative complications (exceeding a severity of Clavien-Madadi score of 2 or higher). No readmission to any hospital within 90 days of the initial surgery, with the exception of planned ostomy removal. No extended length of stay (LOS) beyond the 75th percentile of the entire cohort (i.e., 8 days). 

—

Secondary

Measure	Time frame
Secondary outcomes were perioperative outcome factors, i.e., necessity for ostomy formation, excessive perioperative blood loss as defined by patient weight, duration of surgery, and the incidence of iatrogenic urethral, vaginal or intestinal injury and their corresponding severity according to the ClassIntra classification of intraoperative adverse events.Additional secondary outcomes were the occurrence of postoperative factors and complications within 90 days of the initial surgery, i.e., mortality, anastomotic leakage, surgical site infection, pneumonia, sepsis, hemorrhage, perineal wound dehiscence, ileus, intra-abdominal abscesses, length of hospitalization, postoperative ICU admission, all-cause readmission and all-cause reoperation.	—

Measure

Time frame

Secondary outcomes were perioperative outcome factors, i.e., necessity for ostomy formation, excessive perioperative blood loss as defined by patient weight, duration of surgery, and the incidence of iatrogenic urethral, vaginal or intestinal injury and their corresponding severity according to the ClassIntra classification of intraoperative adverse events.Additional secondary outcomes were the occurrence of postoperative factors and complications within 90 days of the initial surgery, i.e., mortality, anastomotic leakage, surgical site infection, pneumonia, sepsis, hemorrhage, perineal wound dehiscence, ileus, intra-abdominal abscesses, length of hospitalization, postoperative ICU admission, all-cause readmission and all-cause reoperation.

—

Countries

Netherlands

Contacts

Public ContactM.F. Binsbergen

Radboud Universitair Medisch Centrum

maurits.vanbinsbergen@radboudumc.nl+31681354512

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Feb 19, 2026