Wrist and forearm motion study after injury using 4D-CT

Analysis of acute wrist and forearm injuries by 4-Dimensional computed tomographic imaging (UPPER4D) - CARPI 4D

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON58297

Enrollment

Registered

2025-04-23

Start date

2025-10-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wrist, Forearm, Fracture, Kinematics Wrist fracture, forearm fracture

Interventions

During the initial scan, both wrists/forearms will be examined using our 4D-CT method for diagnostic or preoperative purposes. During the second follow-up scan, only the injured wrist or forearm will

Eligibility

Age

16 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients with a one-sided injury to the wrist or forearmPatients are over the age of 16 yearsPatients who are willing and able to give informed consent

Exclusion criteria

Exclusion criteria: Surgical history or other traumatic carpal/forearm injuries. Unable to understand the written informed consent form. Pregnancy. 

Design outcomes

Primary

Measure	Time frame
Correlation of clinical outcomes measured with Patient Reported Outcome Measures: relate observed kinematic patterns to clinical outcomes.	—

Secondary

Measure	Time frame
1.Quantification of motion patterns:Assess relative motion of carpal bones and the forearm in real-time using 4D-CT imaging.Determine key kinematic parameters, including translation and rotation, expressed as movement around and along a Helical Axis of Motion (HAM).2.Characterization of injury-specific kinematics:Identify movement patterns associated with carpal fractures, intercarpal ligamentous injuries, and distal radius malunions.Compare kinematic differences between injured and non-injured wrists/forearms. Evaluate 3D correction and compare kinematic differences before and after surgical intervention.3.Evaluation of fixation stability: assess the stability of fracture fixation or ligamentous reconstruction by comparing kinematic parameters pre- and post-treatment, quantify dynamic differences in patients with stable vs. unstable healing.4.Assessment of technical, functional and patient reported outcomes: evaluate the clinical relevance of 3D-guided corrective osteotomies for symptomatic distal radius malunions.	—

Measure

Time frame

1.Quantification of motion patterns:Assess relative motion of carpal bones and the forearm in real-time using 4D-CT imaging.Determine key kinematic parameters, including translation and rotation, expressed as movement around and along a Helical Axis of Motion (HAM).2.Characterization of injury-specific kinematics:Identify movement patterns associated with carpal fractures, intercarpal ligamentous injuries, and distal radius malunions.Compare kinematic differences between injured and non-injured wrists/forearms. Evaluate 3D correction and compare kinematic differences before and after surgical intervention.3.Evaluation of fixation stability: assess the stability of fracture fixation or ligamentous reconstruction by comparing kinematic parameters pre- and post-treatment, quantify dynamic differences in patients with stable vs. unstable healing.4.Assessment of technical, functional and patient reported outcomes: evaluate the clinical relevance of 3D-guided corrective osteotomies for symptomatic distal radius malunions.

—

Countries

Netherlands

Contacts

Public ContactE.S. Kingma

Amsterdam UMC

e.s.kingma@amsterdamumc.nl020 566 9111

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Feb 3, 2026