Healthy volunteers Healthy volunteers
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy young individuals
Exclusion criteria
Exclusion criteria: A potential participant who meets any of the following criteria will be excluded from participation in this study.Based on self-report and investigators’ judgement: active cardiovascular, respiratory, neurological or autonomic disease; taking anti-hypertensive or other medication that could influence any of the dependent variables; a prior diagnosis of cardiovascular abnormalities or hypertension; weight change more than approximately 15% within the last 6 months; regular use of tobacco products; currently pregnant or lactating; taking any medications other than off-the-shelf supplements. No contraindications for MRI scan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnitude of changes in regional cerebral blood flow during mild controlled changes (~ 5 to 10 mmHg) in peripheral blood pressure compared to those recorded at supine rest. | — |
Countries
Netherlands
Contacts
University of Twente