Gambling disorder Gambling disorder
Conditions
Interventions
Five days of treatment with iTBS, consisting of 50 sessions
10 sessions per day with 50 minutes between-session intervals. iTBS at 90% of the corrected resting motor threshold will be applied to the region in the left DLPFC showing the strongest anticorrelatio
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Moderate to severe gambling disorder (>5 DMS-5 criteria)A wish to stop gamblingAt least one failed treatment attempt
Exclusion criteria
Exclusion criteria: Psychiatric comorbidity that interferes with treatment, e.g. psychosis, acute suicidality, intellectual disability, cognitive disordersTMS contraindications, e.g. seizure disorders or epilepsy, serious head trauma or brain surgery, large or ferromagnetic parts in the head (except dental wire), implanted neurostimulator, pregnancyImplanted metal objects (MRI contraindication)Previous treatment with rTMS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is severity of gambling behaviour after assessed by change in G-SAS score. Other endpoints include mood, gambling-related self-efficacy, behavioural impulsivity, risky decision making, and quality of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include mood, gambling-related self-efficacy, behavioural impulsivity, risky decision making, and quality of life. | — |
Countries
Netherlands
Contacts
Public ContactA.I. Dalhuisen
Radboud Universitair Medisch Centrum
Outcome results
None listed