hemodynamics, hypotension, hemodynamic instability, severity of hypotension Blood circulation, low blood pressure, unstable blood circulation, severity of low blood pressure
Conditions
Interventions
Investigator initiated, prospective, nonrandomized, noninterventional single site data collection study using CE-marked devices
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Participate in the informed consent process and sign/date the approved informed consent form Be = 18 years of age Patient scheduled to undergo endoscopic treatment, patient receiving PCA, or ICU patient
Exclusion criteria
Exclusion criteria: Any significant disfigurement or prior injury to a participant’s finger that is intended to be used for monitoring with the study finger cuffs Known left-right difference in blood pressure Extreme contraction of the smooth muscles in the arteries and arterioles of the lower arm and hand, such as may be present in patients with Raynaud’s disease Patients deemed not suitable for the study at the discretion of the Investigator Treatment with an intra-aortic balloon pump Patient on ECMO Patient on left assist device 8. Known pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this study is to evaluate the impact of pharmacological interventions (such as anesthetics, analgetics, and vasoactive drugs) in the distinguished different hypotensive endotypes | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes are: Time to achieve hemodynamic stability (defined as normalization of blood pressure and heart rate) following pharmacological interventionDuration of sustained hemodynamic (in)stability after the pharmacological intervention;Total administered dose of medication and/or fluids required to achieve hemodynamic stability. | — |
Countries
Netherlands
Contacts
Public ContactCA Otter
Amsterdam UMC
Outcome results
None listed