Locally recurrent rectal cancer Locally recurrent rectal cancer
Conditions
Interventions
This study adds no study interventions to the care that is already being offered to these patients. Patients follow the implemented multidisciplinary palliative care pathway for locally recurrent rect
Sponsors
Catharina Ziekenhuis
Eligibility
Inclusion criteria
Inclusion criteria: 18 years or older.Confirmed diagnosis of locally recurrent rectal cancer after total or partial mesorectal resection for rectal cancer, either by:Histopathology, or;Clinically proven (evidence on imaging in combination with clinical findings) with consensus in MDTWHO performance status 0-3.Determined to be ineligible for curative-intent treatment strategies due to unresectable local disease, distant metastasis, frailty or patient preference.Written informed consent.
Exclusion criteria
Exclusion criteria: Inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is defined as the 1-year local-progression free survival (defined as the absence of local progression of disease based on imaging modalities and/or the absence of progression of clinical complaints associated with tumour progression). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are related to survival, quality of life, symptomatic control and functional outcomes. The following questionnaires are included to assess patient reported outcomes: EORTC QLQ-C15-PAL, EORTC QLQ-CR29 and the EQ-5D-5L. | — |
Countries
Netherlands
Contacts
Public ContactJ.W.A. Burger
Catharina Ziekenhuis
Outcome results
None listed