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Exploring a new electrical stimulation method: Temporal Interference stimulation of the wrist’s median nerve. Volunteer study in the Dutch Brain Interface Initiative (DBI2) project.

Exploring Temporal Interference Stimulation of the Median Nerve: DBI2 study - Exploring Temporal Interference Stimulation of the Median Nerve

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON58153
Enrollment
44
Registered
2025-09-09
Start date
2026-12-07
Completion date
Unknown
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers, healthy participants, no condition Healthy volunteers, healthy participants, no condition

Interventions

Temporal interference stimulation involves the application of two high-frequency sinusoidal currents (carriers) with slightly different frequencies through skin electrodes, producing an amplitude-modu

Sponsors

Eindhoven University of Technology
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Healthy adult between 18 and 64 years old, Right-handed

Exclusion criteria

Exclusion criteria: A potential participant who meets any of the following criteria will be excluded from participation in this study:History of head injury or craniotomyPersonal or family history of neurological or psychiatric disordersMetal implants or implanted electronic devicesSkin sensitivity or allergies that may interfere with stimulationUse of medication during the time of the experimentCurrent pregnancy or possibility of being pregnant

Design outcomes

Primary

MeasureTime frame
The primary endpoint is the change in EEG power at 5 Hz during stimulation compared to baseline and control.

Secondary

MeasureTime frame
Secondary parameters include EMG burst amplitude and spectral power at stimulation frequencies, as well as EEG responses across other stimulation conditions (e.g., 20 Hz envelope). Comparisons between different carrier and envelope frequency conditions will be performed.

Countries

Netherlands

Contacts

Public ContactR.M.C. Mestrom

Eindhoven University of Technology

r.m.c.mestrom@tue.nl0616316831

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 25, 2026