syndromic obesity, genetic obesity inherited tendency to gain weight
Conditions
Interventions
None listed
Sponsors
Amsterdam UMC
Eligibility
Age
2 Years to 99 Years
Inclusion criteria
Inclusion criteria: Informed consent should be given by the patient or their legal representativeConfirmed diagnosis of genetic or syndromic obesity disorder (ORPHA: 77828 or 240371)4 years of age or older
Exclusion criteria
Exclusion criteria: Patients who are deemed poor candidates by the research team for the study based on additional medical concerns that greatly influence energy expenditure, such as a malignant tumor or anorexia nervosaIf the parents/guardians think that the chance is high that their child will not be able to follow the research protocol (for example to lay still for ~20 minutes or to drink the labelled water).Pregnant womenPatients using drugs to treat the obesity or hyperphagiaPatients who do not have a freezer at home
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Energy expenditure, amount of exercise, and body composition (fat percentage). | — |
Secondary
| Measure | Time frame |
|---|---|
| To gain insights in their nutritional intake, weight trajectories and sleep. | — |
Countries
Netherlands
Contacts
Public ContactD. Harskamp
Amsterdam UMC
Outcome results
None listed