Epilepsy Epilepsy
Conditions
Interventions
It will be evaluated whether cortisol and cortisone, measured in hair, is a good method to demonstrate the difference in stress hormones between therapy-resistant and well-controlled epilepsy
Sponsors
Stichting Epilepsie InstellingenNederland
Eligibility
Inclusion criteria
Inclusion criteria: - Diagnosis of epilepsy according to ILAE criteria. - Aged 16 years or older. - Able to provide informed consent. - Sufficient scalp hair (minimum 3 cm length) for analysis. - Either seizure free for = 3 months OR = 4 seizures per month, with a seizure free period of maximal 1 week.
Exclusion criteria
Exclusion criteria: - Any state precluding informed consent completion. - Somatic or psychiatric comorbidities. - Use of systemic corticosteroids within the past 3 months (due to direct impact on cortisol). - Severe scalp dermatological conditions that might affect hair growth or cortisol incorporation. - Major life events in the 6 months before recruitment (marriage, divorce, relocation, birth, new job etc)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair Cortisol and Cortisone Levels in Patients with Therapy-Resistant and Well-Controlled Epilepsy | — |
Secondary
| Measure | Time frame |
|---|---|
| Geen | — |
Countries
Netherlands
Contacts
Public ContactF.N. Saridin
Stichting Epilepsie Instellingen Nederland
Outcome results
None listed