Morton's neuroma, interdigital neuroma, Morton's metatarsalgia, forefoot nerve entrapment Nerve compression in de forefoot
Conditions
Interventions
Sponsors
GOED Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Between 18 and 70 years old;One of the following clinical signs: positive Mulder’s click in the area of the communal and/or interdigital nerve of the foot, a painful webspace or lack of sensation within the interdigital webspace or toes; Thickening of the communal and/or interdigital nerve of the foot between 2 mm – 6 mm on ultrasound;Understand the Dutch language on a proper level.
Exclusion criteria
Exclusion criteria: Younger than 18 years of age or older than 70 years old;Prior surgery for MN or other indications in the same area; Patients with a communal and/or interdigital nerve of the foot smaller than 2 mm or larger than 6 mm;Prior corticosteroid or other injections and/or radiofrequency ablatio for MN within 6 months before inclusionAnticoagulant use;Metabolic syndrome with a BMI >30;Pregnant woman or woman with an active child whish;Patients who are immunocompromised or with a known articular systemic disease; such as rheumatoid arthritis; Patients with prednisone use or immunotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primairy study endpoint will be pain evaluated by the numeric pain rating scale (NPRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secundary study endpoints will be characterisation of blood and PRP for leukocyte and platelet count, ultra-sound evaluation of the interdigital and communal nerves of the foot, the Manchester-Oxford Foot Questionnaire (MOXFQ), Foot Function Index (FFI) and SF-12 Quality of Life Questionnaire. | — |
Countries
Netherlands
Contacts
Public ContactJA van Dongen
GOED Medisch Centrum
Outcome results
None listed