Hypertension, aorto-iliac occlusion High blood pressure, vascular occlusion in abdominal or pelvic artery
Conditions
Interventions
Non-invasive blood pressure measurementInvasive blood pressure measurementPWV/PWA measurementsLaboratory measurements (NT-proBNP, Hemoglobin, Creatinine)
Sponsors
Rijnstate
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age =18 yearsSigned informed consentChronic occlusion in the infrarenal aorta and/or one or both common iliac arteriesTotal lesion length of =30mmClinical indication for endovascular treatment of the pathology (Chronic limb threatening ischemia or disabling intermittent claudication not responding to supervised exercise training)
Exclusion criteria
Exclusion criteria: Patient is unable to understand the study requirements and/ or is unwilling to adhere to the follow-up Juxtarenal pathology (<2cm below the lowest renal artery)Acute occlusion of the target area (Acute Leriche Syndrome)Embolic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to assess changes in arterial blood pressures within 12 months after endovascular treatment of an occlusion of the infrarenal aorta and/or common iliac arteries. | — |
Secondary
| Measure | Time frame |
|---|---|
| To gather the impact of treatment of an occlusion of the infrarenal aorta and/or common iliac arteries on cardiac biomarkers reflective of increased filling pressures at 12 months. To gather the impact of treatment of an occlusion of the infrarenal aorta and/or common iliac arteries on Pulse Wave Analysis (PWA) Pulse Wave Velocity (PWV) at 12 months.To gather the impact of treatment of an occlusion of the infrarenal aorta and/or common iliac arteries on anti-hypertensive medication use at 12 months. | — |
Countries
Netherlands
Contacts
Public ContactD. Veen
Rijnstate
Outcome results
None listed