Cardiac hypertrophy during pregnancy and lactation period Enlargement of the heart during pregnancy and the breastfeeding period
Conditions
Interventions
No intervention or product is applicable. Only the difference between lactation and no lactation after the pregnancy. 
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Pregnant women Age >= 18 years Nulliparous Uncomplicated pregnancy (i.e. no gestational diabetes or hypertensive disorder of pregnancy).
Exclusion criteria
Exclusion criteria: Presence of comorbidities or disease (i.e. hypertension, diabetes, obesity) Twin/multiple pregnancy Smoking or consumption of drugs and/or alcohol during pregnancy Planned to give breastfeeding in combination with infant formula from the beginning of the lactation period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective: Determine the changes in cardiac size as the result of breastfeeding after pregancy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Objective(s): Identify biomarkers which are associated with lactation-related cardiac hypertrophy. Identify the role of maternal/obstetric/neonatal outcomes in relation to lactation and cardiac function. | — |
Countries
Netherlands
Contacts
Public ContactP Meer
Universitair Medisch Centrum Groningen
Outcome results
None listed