Multiple Sclerosis
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Diagnosis of MS Age 18-60 Ability to perform the foot-tapping task Ability to walk at least 20 meters (with or without walking aid)
Exclusion criteria
Exclusion criteria: - Medication use with dimethyl fumarate, fingolimod or alemtuzumab - MS relapse 6 weeks before the start of the study - Change in medication within 6 weeks of the start of the study - Having a psychiatric disorder - Having a neurological disorder other than MS - Having cognitive or communicative problems that makes it hard to follow instructions - Had an infection in the last month - Received a vaccination in the last 14 days - Pregnant or pregnancy in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scores from the fatigue questionnaires and decline in amplitude and frequency from the performance fatiguability test will be correlated to the level of CD4 CTLs from the blood samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle activation patterns measured by EMG, distance walked on 6MWT and voluntary muscle activation. | — |
Countries
Netherlands
Contacts
Public ContactN Dreijer
Universitair Medisch Centrum Groningen
Outcome results
None listed