PROSE: Prediction of Seizures in Epileptic Patients

Prospective prediction of seizures in epileptic patients through analysis of VOCs in exhaled air by means of hand-held electronic nose technology - PROSE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON57971

Enrollment

Registered

2025-04-04

Start date

2025-11-10

Completion date

Unknown

Last updated

2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy, Epileptic Seizures Epilepsy, Epileptic Seizures

Interventions

BreathPass (e-nose)

Eligibility

Age

16 Years to 64 Years

Inclusion criteria

Inclusion criteria: To be admitted to SEIN or Kempenhaeghe for video-EEG recoding; to be diagnosed with epilepsy; having a high seizure frequency;  with a history of tonic/clonic seizures; being mentally competent

Exclusion criteria

Exclusion criteria: Patients with psychogenic nonepileptic seizures will be excluded.

Design outcomes

Primary

Measure	Time frame
Primary study parameters: Exhaled breath profiles obtained by sampling breath using eNose technology compared with the presence of an epileptic seizure and the time to seizure.	—

Secondary

Measure	Time frame
Secondary study parameters: Breath profiles from exhaled air samples (eNose technology) compared with the presence of epilepsy versus non presence of the disease (control group).	—

Countries

Netherlands

Contacts

Public ContactR.D. Thijs

Stichting Epilepsie Instellingen Nederland (SEIN)

rthijs@sein.nl023-5588940

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Mar 20, 2026