Serous endometrial intra-epithelial carcinoma (SEIC) Endometrial cancer
Conditions
Interventions
Not applicable.
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Any diagnosis other than a non-invasive serous intraepithelial endometrial lesion, including: - Endometrioid carcinoma - Clear-cell carcinoma - Serous carcinoma with invasion - Carcinosarcoma - Endometrial hyperplasia or endometrial intraepithelial neoplasia (EIN)Cases in which histopathology shows myometrial or stromal invasion, even if previously labelled SEIC.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Diagnosis with a different type of endometrial neoplasm or invasive carcinoma. - Previous and/or current treatment for another malignancy (<2 year before diagnosis of SEIC).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival (PFS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival (OS), disease related symptoms (measured by QLQ-EN24 questionnaire), health related QoL (measured by EORTC QLQ-C30 questionnaire), grade 3-4 adverse events. | — |
Countries
Netherlands
Contacts
Public ContactH.J. Beekhuizen
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed